Automated solid phase synthesis of oligoarabinofuranosides.
نویسندگان
چکیده
Automated solid phase synthesis enables rapid access to the linear and branched arabinofuranoside oligosaccharides. A simple purification step is sufficient to provide the conjugation ready oligosaccharides in good yield.
منابع مشابه
Microwave-assisted Solid-phase(SPPS) and Solution-phase (SPS) Synthesis of Biological Dipeptide ((β-alanine-L histidine)
Peptides have shown Promising effect as pharmaceutics with the potential to treat a widevariety of diseases. Peptides are mostly synthesized by biological technology or chemicalmethods. Solution phasepeptide synthesis (SPS) and solid phase peptide synthesis (SPPS) aretwo major chemical techniques for peptidesproduction.In this research, the synthesis ofdipeptde(β-alanine-L-histidine)wasexamined...
متن کاملCombination of automated solid-phase and enzymatic oligosaccharide synthesis provides access to α(2,3)-sialylated glycans.
A synthetic strategy combining automated solid-phase chemical synthesis and enzymatic sialylation was developed to access α(2,3)-sialylated glycans.
متن کاملInvestigation and comparison of calcium aluminate phases obtained by three methods of sol-gel (with EDTA), sol-gel (without EDTA) and solid-phase synthesis
In this study, we investigate calcium aluminate phases that were prepared by three different solid phase synthesis methods and a sol-gel method (with and without EDTA). The purpose of this study is to compare these three methods in terms of achieving higher purity, optimal phase and complexity in the production of the final product. Comparing the results, we found that the sol-gel method is mo...
متن کاملAutomated solid-phase synthesis of oligosaccharides.
Traditionally, access to structurally defined complex carbohydrates has been very laborious. Although recent advancements in solid-phase synthesis have made the construction of complex oligosaccharides less tedious, a high level of technical expertise is still necessary to obtain the desired structures. We describe the automated chemical synthesis of several oligosaccharides on a solid-phase sy...
متن کاملAutomated solid-phase synthesis of oligosaccharides containing sialic acids
A sialic acid glycosyl phosphate building block was designed and synthesized. This building block was used to prepare α-sialylated oligosaccharides by automated solid-phase synthesis selectively.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Chemical communications
دوره 49 40 شماره
صفحات -
تاریخ انتشار 2013